Alcohol causes different cancers

The more alcohol you drink, the higher your risk of developing at least seven different types of cancers. Drinking small or moderate amounts of alcohol was associated with increased risks for esophogeal, mouth, voice box, liver, stomach, pancreas and breast cancers, and is responsible for more than five percent of cancers and cancer deaths worldwide.

The American Society of Clinical Oncology ASCO has never addressed the link between alcohol and cancer, but is now underscoring the importance of controlling the risk of alcohol consumption to reducing the risk of cancer. While the ASCO does suggest strategies for cutting back on drinking, it also advocates for temperate use of alcohol, rather than recommending give up drinking.

The Centres for Disease Control and Prevention CDC recommends that women should not have more than one drink a day or eight drinks a week. Men drink two drinks a day, or 14 a week. There has been some debate over whether alcohol or other compositions of various alcoholic beverages are cancer-causing. There is an associations between alcohol drinking and cancer risk. Alcohol does not affect each part of the body in the same carcinogenic way.

For head and neck and esophageal cancers, alcohol's breakdown product- acetaldehyde, which is an established carcinogen touches the tissues directly as drinker swallows an alcoholic drink and causes cancer. Liver cancer is caused by cirrhosis, which is caused by drinking. When cirrhosis develops, healthy liver cells are replaced by damaged scar tissue cells, which can become cancer cells. It interferes with the absorption of folate, which leads to development of colon cancer.

When a woman’s estrogen levels become abnormally high, the hormone puts her at higher risk for breast cancer. Alcohol has been shown to increase estrogen levels, thus putting women at greater risk of breast cancer. In fact, ASCO reports that women who drank even one drink of beer or wine which have significantly lower alcohol contents than liquors were five percent more likely to develop premenopausal breast cancer, and nine percent more likely to develop the cancer after menopause.
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Mavyret for treating chronic hepatitis C

Mavyret is a prescription medicine used to treat adults with chronic hepatitis C virus HCV genotypes 1, 2, 3, 4, 5 or 6 infection without cirrhosis or with compensated cirrhosis. It contains two medicines: glecaprevir and pibrentasvir.

If you have ever had hepatitis B virus infection, the hepatitis B virus could become active again during or after treatment of hepatitis C virus with Mavyret. Hepatitis B virus becoming active again may cause serious liver problems including liver failure and death.

The common side effects are headache and tiredness.

The active ngredients in Mavyret are: glecaprevir and pibrentasvir

Inactive ingredients: colloidal silicon dioxide, copovidone (type K 28), croscarmellose sodium, hypromellose 2910, iron oxide red, lactose monohydrate, polyethylene glycol 3350, propylene glycol monocaprylate (type II), sodium stearyl fumarate, titanium dioxide, and vitamin E (tocopherol) polyethylene glycol succinate.
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Carospir for treating hypokalemia

Carospir (spironolactone) is a potassium-sparing diuretic water pill that prevents body from absorbing too much salt and keeps potassium levels from getting too low.

Spironolactone is used to diagnose or treat a condition of too much aldosterone in the body. Aldosterone is a hormone produced by adrenal glands to regulate the salt and water balance in the body.

Spironolactone also treats fluid retention (edema) in people with congestive heart failure, cirrhosis of the liver, or a kidney disorder known as nephrotic syndrome.

 Spironolactone is used for treating or preventing low potassium levels in the blood. Avoid  spironolactone if you are allergic to the drug, have kidney disease, or if you are unable to urinate.

Common side effects are: mild nausea, vomiting, diarrhea, breast swelling or tenderness, dizziness, headache, mild drowsiness, leg cramps and impotence hives, difficulty breathing, swelling of face, lips, tongue, or throat.
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Vosevi drug for hepatitis treatment

Hepatitis C is a viral infection that can cause inflammation and serious damage to the liver. The virus is spread through human contact with infected blood.

The U.S. Food and Drug Administration (FDA) has approved Vosevi (sofosbuvir 400 mg/velpatasvir 100 mg/voxilaprevir 100 mg) tablets, a single-tablet regimen for the treatment of adults with chronic hepatitis C virus (HCV).

Vosevi is a prescription medicine used to treat adults with chronic (lasting a long time) hepatitis C virus (HCV) infection without cirrhosis or with compensated cirrhosis who have:
genotype 1, 2, 3, 4, 5, or 6 infection and have previously been treated with an HCV regimen containing an NS5A inhibitor.

Do not combine Vosevi with any medicines that contain rifampin (Rifater, Rifamate, Rimactane, Rifadin).
Before taking Vosevi

The drug can cause serious side effects, like: Hepatitis B virus (HBV) reactivation, slow heart rate, fainting,
dizziness, shortness of breath, chest pains, confusion, memory problems, headache, tiredness, diarrhea, and nausea.
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Dangers of stress

A stressful life increases the thickness of the artery walls, leading to high blood pressure and heart disease.

It also increases the production of cortisol. Researchers used high-tech MRI scanners to examine the brains, hearts and bone marrow of nearly 300 patients.

They discovered that people with higher activity in the amygdala region of the brain, the part associated with stress, were 59 percent more likely over the next 3.7 years to develop heart failure.

Stress has been linked to illnesses like cancer, lung disease, bone loss and cirrhosis of the liver.


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Tea or coffee can protect your liver

According to a new study published in the Journal of Hepatology, researchers found that drinking coffee and herbal tea may protect against liver fibrosis.

Unhealthy habits, sedentary lifestyle and consumption of processed foods cause non-alcoholic fatty liver disease NAFLD.

Coffee has health benefits on liver enzyme elevations, viral hepatitis, NAFLD, cirrhosis, and liver cancer.

Data was gathered on 2,424 participants of the Rotterdam study, a large population-based cohort study including participants 45 years or older living in a suburb of Rotterdam, The Netherlands.

All participants underwent an extensive physical work-up, including data collection for anthropometrics, blood sampling, hepatological imaging using abdominal ultrasound and Fibroscan®, which quantitatively measures liver stiffness.

Coffee and overall tea consumption was divided into three categories: none, moderate (0-3 cups per day), and frequent (more than 3 cups per day). Tea consumption was categorized by herbal, green, or black tea and further into none (0) or any (>0) consumption.

Researchers discovered that frequent coffee consumption was significantly associated with less scarring of the liver, independent of lifestyle, metabolic, and environmental traits.

When they looked at the whole range of liver stiffness values, they found that both frequent coffee and any herbal tea consumption, even in small amounts, were significantly associated with lower liver stiffness values.

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