Zika virus infection can cause brain damage and sometimes death of fetus in the womb, it infects the fetus by manipulating the normal barrier to infection in the body.
Exposure to zika virus activated genes related to autophagy, the virus multiply in the placenta, autophagy process in the placenta promotes zika's survival and it infects the placental cells.
With this suppression, their is less damage and the fetuses grow normally.
The malaria drug protects the fetus from the zika virus even when the virus is still present in the mother. It effectively blocks viral transmission to the fetus by interfering with the process of zika virus infection transmission and protects fetus from viral infection.
Hydroxychloroquine suppresses the autophagy response, this reduces the virus in the fetuses and placentas.
With this suppression their is less damage and the fetuses grow normally.
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