Kidney transplant patients are at greater risk of developing melanoma than the general population and risk factors are being older, male and white.
Lifelong immunosuppressive therapy is among the complex lifestyle changes faced by renal transplant patients. The type, intensity and duration of immunosuppressive therapy contribute to the risk of developing skin cancer, such as melanoma
Immunosuppressant drugs used to suppress and reduce the strength of the body's immune system and to make the body accept the transplanted organ.
Most of the patients with melanoma were men. Almost all of the patients with melanoma were white and they were more likely to be taking the common immunosuppressants cyclosporine or sirolimus than those without melanoma.
The group of patients who developed melanoma also had a greater proportion of living donors.
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