The bitter taste receptors that was found on uterine muscle could be use to examined the onset of labor, both at term and preterm.
Researchers attached strips of human and mouse uterine myometrium tissue to a machine that measured their contraction efforts.
The researchers first exposed the tissue to native hormones such as oxytocin and chemical compounds to make it contract, mimicking normal or premature labor.
They then exposed the tissue to bitter substances. Activating bitter taste receptors in the uterus relaxed the contracted uterine muscle tissue totally than the use of drugs.
The researchers also discovered that giving mice bitter substances before they showed any premature contractions prevented them from having early deliveries. This can also prevents preterm labour in human.
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