Gastric cancer developed from the lining of the stomach, common symptoms are: heart burn, nausea and abdominal pain.
Experiments analyzed whole tomato lipophilic extracts for their ability to tackle various neoplastic features of gastric cancer cell lines.
Extracts of both the San Marzano and
Corbarino tomato varieties were able to inhibit the growth and cloning behavior of malignant cells.
Treatment with the whole tomato extracts affected key processes within the cells preventing their migration ability, hindering cell cycle through the modulation of retinoblastoma family proteins and specific cell cycle inhibitors, and inducing cancer cell death through apoptosis.
Gastric cancer is the fourth most common type of cancer worldwide and has been associated with genetic causes, Helicobacter pylori infection, and eating habits, such as consumption of smoked and salted food. Different tomato components have also been analyzed for their ability to counteract tumor growth.
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