Anorexia is an eating disorder that makes people to lose more weight than is considered healthy for their age and height.
People with this disorder are afraid of gaining weight, even when they are underweight. They may diet, exercise or use different methods to lose weight.
The study included genome-wide analysis of DNA from 3,495 individuals with anorexia nervosa and 10,982 unaffected individuals.
If particular genetic variations are significantly more frequent in people with a disorder compared to unaffected people, the variations are said to be related with the disorder.
Associated genetic variations can serve as powerful pointers to regions of the human genome where disorder-causing problems reside, according to the National Human Genome Research Institute.
Genome-wide significant locus for anorexia nervosa on chromosome 12, in a region previously shown to be associated with type 1 diabetes and autoimmune disorders.
Anorexia nervosa was significantly genetically correlated with neuroticism and schizophrenia. There is strong
genetic correlations with various metabolic features including body composition (BMI) and insulin-glucose metabolism.
No comments:
Post a Comment