Links between colonoscopy and appendicitis

Colonoscopy is the examination of the colon- the large intestine by a gastroenterologist. It is is associated with increased risk of appendicitis, there is an evidence to suggest that colonoscopy can cause appendicitis up to one week after colonoscopy in some patients. The rate of appendicitis and appendectomy in the first week after a colonoscopy is high.

The colon must be completely cleaned before colonoscopy, if bacteria within the colon are altered as the bowel is prepared prior to colonoscopy in ways that increase the likelihood of inflammation, or if the increased air pressure caused by colonoscopy, it may have effects on the colonic mucosa that can predispose people to appendicitis.

Appendicitis is a condition when the appendix becomes inflamed and filled with pus, colonoscopy is valuable and the appendicitis rate is still very low, right-lower abdominal pain after colonoscopy may be a sign of appendicitis.
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Clenpiq for Colonoscopy Prep

Food and Drug Administration FDA has granted approval of Clenpiq (sodium picosulfate, magnesium oxide, and anhydrous citric acid) oral solution for cleansing of the colon in adults undergoing a colonoscopy. Colonoscopies can reduce the incidence of colorectal cancer and deaths associated with this disease. Successful bowel prep is critical for gastroenterologists to clearly see the inside of the colon during a colonoscopy.

The sheer volume of a prescribed bowel prep solution can be a barrier for some patients to adequately complete their prep regimen, leading to suboptimal visualization of the colon, A ready-to-drink, low volume colonoscopy prep in a pre-mixed oral solution is an excellent start to prepare patients for this important procedure to detect and prevent colorectal cancer.

Clenpiq is a ready-to-drink cranberry-flavored, dual-acting, combination of sodium picosulfate, a stimulant laxative, and magnesium oxide and anhydrous citric acid, which forms magnesium citrate, an osmotic laxative indicated for cleansing of the colon as a preparation for colonoscopy in adults.

Clenpiq is contraindicated in the following conditions: patients with severe renal impairment (creatnine clearance less than 30mL/minute), gastrointestinal obstruction or ileus, bowel perforation, toxic colitis or toxic megacolon, gastric retention, or in patients with a known hypersensitivity to any of the ingredients in Clenpiq.

Patients should be advised to hydrate adequately (before, during and after use of Clenpiq), and post-colonoscopy lab tests should be considered if a patient develops significant vomiting or signs of dehydration, including orthostatic hypotension, after taking Clenpiq. Patients with electrolyte abnormalities should have them corrected before treatment. The most common adverse reactions in those trials were nausea, headache, and vomiting.
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Prevention of colon cancer

Colon is the lowest part of the digestive system, colon cancer is the growth of cancer from the colon or rectum. Common symptoms of colon cancer are: fatigue, weight loss, blood in the stool and change in bowel movement.

Colonoscopy is one of the best way to treat colon cancer if it is discovered early. This type of cancer can develop without symptoms it is good to go for regular screening for early detection.

This cancer is common in people with sedentary lifestyle and tobacco smokers. Eating food low in fibre, high in fat, calories and preservatives may increase the risk of colon cancer.

It can be prevented by:
• regular screening
• regular exercise
• maintaining healthy weight
• eating balanced diet
• drinking enough water
• avoiding  alcohol and tobacco products