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Saturday, 22 April 2017
Scientists discovered cancer-related gene mutation
Cancer starts with production of abnormal cell growth of genetic mutation.
Researchers from University of Maryland led by Thomas Peterson examined similar mutations that are all over genome.
They used genetic data to examined subcomponents of protein domain and discovered that each domain carries out different roles and still share the same protein domain.
Researchers focused on mutations in one region of specific genes and mutations in similar region across families of protein.
Data about somatic variants from 5,848 patients was collected with some patients having 20 different types of cancers.
Detecting variants for tumorigenesis will expose the cause of tumour progression leads to production of drugs for families of genes that shows similar variation at functional level.
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