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Thursday, 13 April 2017
Komodo dragon blood may become an antibiotics
Harmful microbes are developing resistance to drugs that used to kill them, scientists are looking for powerful antibiotics that can destroy bacteria.
The bacterium Clostridium difficile is responsible for about 250,000 infections and 14,000 death, this makes it a threat to human.
Komodo dragon may be the new source of antibiotics because of its special qualities according to Van Hoek and colleagues.
Reptiles are strong animals, Komodo dragon can eat decayed food without any effect, peptide VK25 in its blood contains antimicrobial properties that can prevent biofilms.
The researchers rearrange two amino acids in its blood-VK25 to make it more effective and discovered new synthetic version of the peptide called DRGN-1
The team tested DRGN-1 on mice wounds that had Pseudomonas aeruginosa and Stephlococcus aureus, the synthetic peptide destroyed the biofilm of the wounds and the two bacterial strains.
This positive result will make it effective in healing wounds and an effective antibiotics for human.
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