How to prevent type 1 diabetes

White blood cells make antibodies against pathogens or other invaders in healthy people. Pancreatic beta cells produce insulin, the hormone that provides fuel to the body's cells by transporting glucose.

 B lymphocytes plays a major role in activating the autoreactive T cells (T lymphocytes) that then destroy the pancreatic beta cells leading to type 1 diabetes.

These damaged cells fail to take glucose into cells, the glucose build up in the blood can damage nerves, blood vessels and organs.

The researchers used a gene manipulation approach to identify a potential metabolic target that would eliminate the B cells that initiate diabetes.

They demonstrated that non-obese diabetic (NOD) mice treated with a specific (AID/RAD51) pathway inhibitor had more of B cells that were capable of suppressing diabetogenic T cell and reduced T1D development.

Antibody production of B cells turn on the gene known as activation-induced cytidine deaminase (AID), which acts as a molecular scissors that cut the chromosomes within the B-cell.

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How bacteria in your mouth may suggest your cancer risk

Bacteria are tiny microorganisms that exist in group, human mouth can have more than 5 billion different bacteria; some are useful while some are harmful to human health.

Jiyoung  Ahn, an associate professor of epidemiology at the New York University school of medicine said people have microbes from the same five main group of bacteria but it may vary from one genus to another.

She said the variability of these bacteria in the month may be linked to people's cancer risk, her team of researchers discovered that people that have higher Porphyromonas  a type of bacteria are at risk of pancreatic cancer.

Earlier research shows that bacteria in the mouth can go throughout the body, interact with receptors on the cells and leads to cancer.