The U.S. Food and Drug Administration (FDA) has approved Erleada (apalutamide), a next-generation androgen receptor inhibitor for the treatment of patients with non-metastatic castration-resistant prostate cancer. Erleada is a prescription medicine used to treat prostate cancer that has not spread to other parts of the body and no longer responds to a medical or surgical treatment that lowers testosterone.
Before you start treatment, tell your healthcare provider about all your medical conditions, including if you have a history of seizures, brain injury, stroke, or brain tumors. If you have a partner who is pregnant or may become pregnant. Men who are sexually active with a pregnant woman must use a condom during and for three months after treatment.
Erleada treatment can cause bones and muscles to weaken and may increase risk for falls and fractures. Falls and fractures have happened in people during treatment with Erleada. Falls were not caused by loss of consciousness (fainting) or seizures. Your healthcare provider will monitor your risks for falls and fractures during treatment.
Seizure-if you take Erleada, you may be at risk of having a seizure. You should avoid activities where a sudden loss of consciousness could cause serious harm. Tell your healthcare provider right away if you have a loss of consciousness or seizure. Your healthcare provider will stop Erleada if you have a seizure during treatment.
The most common side effects include:feeling very tired, high blood pressure, rash, diarrhea, nausea, decreased appetite, weight loss, joint pain, fall, hot flash, bone injury (fracture), swollen hands, ankles and feet. Erleada may cause fertility problems.
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