Migraine are an integrated mechanism by which the brain protects and repairs itself. Migraine can be triggered by diet, stress, sleep disruption, noise and air pollution. It can increase brain oxidative stress, an imbalance between the production of free radicals and the ability of the body to counteract their harmful effects.
Oxidative stress is a useful signal of impending harm because a number of unfavorable conditions in the brain can give rise to it, targeting oxidative stress might prevent or preempt migraines. An interruption in blood supply each of the components is protective: strengthening antioxidant defenses, lowering the production of oxidants, lowering energy requirements and, especially, releasing growth factors into the brain that protect existing neurons and support the birth and development of new neurons.
There are feedback loops between these components of a migraine attack that tie them together into an integrated system, migraine attacks are not triggered by oxidative stress, they actively protect and repair the brain from it. The pain, nausea, and sensitivity to light and sound, fever and pain, or cough are not the disease itself but part of the body's defense against migraine.
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