After a severe traumatic injury, the composition of a patient's intestinal bacteria changes and this could affects patient's prognosis. The gut microbiome experiences a depletion in the presence of some bacteria and an increase in the presence of others came from a small investigation, involving critically injured adults.
Stool samples were collected from each person three times: when they were admitted to the hospital, and then 24 and 72 hours later. The samples were compared with those from 10 other patients who had not sustained traumatic injury.
Samples taken at the time of admission were similar in both groups. But within 24 hours, differences started to show, the investigators found. By 72 hours, three types of bacteria were depleted in the traumatic injury group, relative to the non-injury group, and the levels of two other types of bacteria had risen.
Rapid alterations in intestinal microbiota represent a critical and unrecognized phenomenon that may influence clinical course and outcomes after severe trauma. The intestinal bacterial composition could in some way be critical to patient outcomes after a traumatic injury. This could create the way towards interventions, such as administering probiotic regimens that might improve patient outcomes after injury.
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