IVF increases the risk of premature birth

In vitro fertilization IVF increases the risk of women giving birth prematurely. Ten per cent of women who conceived through fertility treatment gave birth before 37 weeks, which is considered premature. However, those born before 37 weeks are still more likely than full-term babies to suffer from a range of long-term problems, including cerebral palsy, and developmental conditions such as ADHD. IVF may trigger changes in the placenta, which increases the risk of premature birth.

Experts believe that freezing the embryo first and then implanting it later, rather than doing everything in the same menstrual cycle, may offer protection against the risk. Women who had IVF were 63 per cent more likely to give birth before 37 weeks than those who had conceived naturally. Some studies indicate that ‘sub-fertile’ women who have trouble conceiving tend to be biologically predisposed to premature birth because implantation process is compromised slightly by IVF.

The removal of eggs during fertility treatment could damage the womb’s lining. If implantation could be delayed after egg collection – as enabled by freezing embryos, then the womb could be given time to heal, leading to a better chance of pregnancy. The potential benefits of freezing embryos are highly dependent on the skills of different IVF clinic's. If implantation could be delayed by a month or two after egg collection, premature birth could be prevented.
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