Source of ageing process

Genes belong to a process called autophagy - this one of the cells most critical survival processes, it promotes health and fitness in young worms but drive the process of ageing later in life.

 Promoting longevity by closing down autophagy in old worms improves neuronal and subsequent whole body health. Getting old happens to every species, natural selection results in the fittest individuals for a given environment surviving to breed and pass on their genes to the next generation.

The more fruitful a trait is at promoting reproductive success, the stronger the selection for that trait will be. Some genes encourage ageing while still being essential for development, there are series of genes involved in regulating autophagy, which accelerate the ageing process.

The process of autophagy is a critical recycling process in the cell. Autophagy is known to become slower with age and closing it down in the initiation of the process allows the worms to live longer.

There are severe negative consequences when it breaks down and then you are better off bypassing it all together. In young worms, autophagy is working properly and is essential to reach maturity but after reproduction, it begins to malfunction causing the worms to age.

 By inactivating autophagy in the neurons of old worms they were able to prolong the worms life and increased the total health of the worms. Turning autophagy off only in one tissue and the whole animal gets a boost. The neurons are much healthier in the treated worms and keeps the muscles and the rest of the body in good shape.
          haleplushearty.blogspot.com

Paternal vitamin D levels determined the health of children

Men with good levels of vitamin D before producing children are more likely to have healthy children.

According to a new study by University College Dublin, which found a direct link between a child's height and weight at five years old, and their father's pre-conception vitamin levels.

Researchers analyzed data on 213 father-child pairs from the Lifeways Cross-Generation Cohort Study - a unique longitudinal database in Ireland - when the children were aged five and nine years old.

They carried out a questionnaire to assess a number of factors.
These included paternal age, height, weight, maternal age, vitamin D and energy intake height, and weight.

They also analyzed the child's sex, age, vitamin D and energy intake, and summer outdoor physical activity.

Compiling all the data, they discovered that paternal vitamin D intake directly impacted child's height and weight in their early years.

Father's nutrition status may somehow influence the health, quality and function of their germ cells which are involved in reproduction.

       haleplushearty.blogspot.com

Hot flashes is linked to heart disease

More than 60 percent of women experience frequent and severe hot flashes, research indicates that hot flashes occur during late reproductive years and it can continue for more than ten years.

The researchers examined 272 women aged between 40 and 60 years, some of them have hot flashes daily while some do not. These women do not smoke and had no record of cardiovascular disease.

The women were monitored for physiologic sign of hot flashes in ambulatory care and diary monitoring.

Researchers tested their blood and endothelial function by an ultrasound measurement of the flow-mediated dilation of their brachial artery.

It was discovered that their is no link between hot flashes and vascular dysfunction in  women between 54 and 60 years. 

Younger women between the age of 40 and 53 years with regular hot flashes may have poorer endothelial function. Dr. JoAnn Pinkerton executive director of the North America Menopausal Society said hot flashes have been linked to cardiovascular, bone and brain health.