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Showing posts with label Neurotransmitter. Show all posts
Showing posts with label Neurotransmitter. Show all posts
Monday, 27 November 2017
Anger causes untimely death
Researchers have discovered that angry men aged 20 to 40 were one-and-a-half times more likely to be dead 35 years later than those who were calmer. They believe this is due to a number of factors linking stress to physiological damage. The frequent release of adrenaline during periods of stress damages DNA, which could lead to life-threatening illnesses such as multiple sclerosis.
Feelings of anger produce a heightened response in the amygdala, the part of the brain associated with survival instincts. Angry emotions prompt the amygdala to signal a heightened state of anxiety to the rest of the brain and the body, increasing blood flow to the limbs and heart, which makes relaxation impossible.
Those exposed to anger-inducing stimuli without discussing how it made them feel are more likely to experience insomnia than those who engage in an emotional ‘debrief’, according to neuroscientists. Writing the cause of anger frees up the space in the head, dampening the fear response and encouraging relaxation.
Emotions such as excitement or anger result in the release of stress hormones cortisol, adrenaline and testosterone, which put the body into flight-or-flight mode. The chemical surge increases blood flow to the brain and triggers the swelling of both blood vessels and nerves surrounding the brain. The pressure can result in tension and headaches.
Highly hostile individuals performed significantly worse on a simple inhalation task than those who were rated less hostile. When you are angry, neurotransmitters and hormones are sent through the bloodstream which, in turn, increase both the heart rate and muscle tension. Frequent occurrence of this reaction puts a strain on neurons in the hypothalamus, the brain’s ‘stress control centre’, meaning that it becomes harder for the neurons to switch off. And the ‘happy hormone’ serotonin is significantly depleted in some aggressive individuals.
Too much cortisol in the body – released by adrenal glands during angry outbursts can cause an imbalance in blood sugar, repress the thyroid and even decrease bone density. When released initially, cortisol triggers an anti-inflammatory response by the immune system, but prolonged increase of the hormone makes the body more susceptible to viruses. As blood pressure rises thanks to a surge in adrenaline, the heart beats faster, increasing the risk of potentially fatal abnormal heart rhythms. Adrenaline also signals for the release of platelets, which can trigger blood clots or block arteries – particularly dangerous if arteries are restricted by a build-up of cholesterol.
Studies have shown that men in particular who score highly on trait anger scales are three times more likely to suffer from general heart disease. Once the ‘fight or flight’ signal has been issued by the brain, blood supply is directed to areas needed for action such as the limbs. That means blood supply to the digestive system is reduced, with a reduced amount of oxygen provided to keep vital ‘good’ bacteria in the gut alive. A dampened immune system can lead to a weakened gut lining, increasing vulnerability to harmful bacteria entering the area.
Heightened stress reduces the amount of available glucocorticoids -the hormone involved in the synthesis of the skin-plumping compound collagen. Lack of collagen contributes towards saggy, wrinkled skin. The weakened immune system caused by stress responses increases inflammatory reactions to pathogens underneath the skin.
Enhanced periods of anger disrupt the skin-barrier function, making it easier for allergens to penetrate and resulting in skin conditions such as dermatitis and psoriasis. Repressing, rather than expressing anger puts you at an higher risk of developing health problems. This increased risk of hypertension for angry individuals who tended to keep their anger below a level of consciousness. By repressing emotion, excess stress hormones remain in the emotion-processing areas of the brain for longer period making physical reactions chronic.
haleplushearty.blogspot.com
Labels:
Adrenaline,
Amygdala,
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Arteries,
Blood flow,
Cholesterol,
Cortisol,
DNA,
Hypothalamus,
Insomnia,
Multiple sclerosis,
Neuroscientists,
Neurotransmitter,
Physiological damage,
Thyroid
Thursday, 28 September 2017
Immune cells hinder metabolism in adult
Older people do not burn the energy stored in fat cells as efficiently as younger people, this leads to the accumulation of harmful belly fat. The underlying cause for this unresponsiveness in fat cells was unknown.
Researchers discovered a new type of macrophage that resides on the nerves in belly fat. These nerve-associated macrophages become inflamed with age and do not allow the neurotransmitters, which are chemical messengers, to function properly.
The researchers also isolated the immune cells from fat tissue of young and old mice, and then sequenced the genome to understand the problem.
They discovered that the aged macrophages can break down the neurotransmitters called catecholamines, and thus do not allow fat cells to supply the fuel when needed. Lowering a specific receptor that controls inflammation, the NLRP3 inflammasome, in aged macrophages, the catecholamines could act to induce fat breakdown, similar to that of young mice.
Researchers blocked an enzyme that is increased in aged macrophages, restoring normal fat metabolism in older mice, monoamine oxidase and MAOA, is prevented by existing drugs in the treatment of depression. When immune cell interact with nerves and fat cells to reduce belly fat, this enhance metabolism, improve performance and belly fat loss in older people.
haleplushearty.blogspot.com
Saturday, 29 July 2017
Smoking causes anxiety and phobia
Smoking may make smokers more vulnerable to suffering from phobias and other types of chronic fear like post-traumatic stress disorder PTSD.
Scientists have discovered that smoking tobacco can impair the brain's ability to repress fear-related memories, making smokers unable to deal with fear and anxiety after a traumatic experience.
Dangerous chemicals in tobacco may interfere with neurotransmitter and neurons in the brain. Neurotransmitters are responsible for controlling fear.
Smoking is a common habit among people who suffer from post traumatic stress disorder PTSD. The more people smoke, the less they were able to inhibit fear response.
Smoking impairs the repression of fear related memories, when there is no danger. Long-term smoking leads to higher deficit in inhibiting fear responses.
Smoking changes neurotransmitter balances in the brain, which are necessary for successful safety learning.
Enhancing dopamine in the brain and putting an end to tobacco smoking can put an end to fear associated with smoking.
haleplushearty.blogspot.com
Saturday, 22 July 2017
Dangers of high fat diet in pregnancy
High-fat diet during pregnancy affects the development of the brain and endocrine system of fetus. Unhealthy diet during pregnancy can increase the risk of mental health disorders like anxiety and depression in children.
Fetuses exposed to a high-fat diet will have greater cases of anxiety, high fat exposure impaired the development of neurons containing serotonin, a neurotransmitter that's critical in developing brains.
High fat diet in pregnancy contributes to neuropsychiatric disorders like attention deficit hyperactivity disorder ADHD spectrum disorders, bipolar
disorder, depression, eating disorders, schizophrenia, anxiety and depression in children.
haleplushearty.blogspot.com
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