When pregnant women take the common diabetes medication metformin throughout pregnancy, it can positioned their kids at increased hazard of having weight problems or obese. Many pregnant women are taking metformin to deal with gestational diabetes or polycystic ovary syndrome PCOS. PCOS increases the risk of developing diabetes and other metabolic problems.
When pregnant women with PCOS or gestational diabetes take metformin, it crosses the placenta and passed to the fetus. According to Liv Guro Engen Hanem, M.D., of the Norwegian University of Science and Technology in Trondheim, Norway, the children of pregnant women who took metformin or placebo during pregnancy are at risk of weight gain.
Researchers invited parents of 292 children who participated in previous randomized scientific trials to be part of the study. In the preceding trials, pregnant women with PCOS were assigned to take either metformin or a placebo during pregnancy, the researchers wound up reviewing frame mass index BMI and other measurements for 161 children born following the advance studies.
At age four, the children whose mothers had been randomized to metformin at some point of being pregnant tended to weigh greater than the children whose mother took the placebo despite the fact that metformin did not appear to have an effect on birth weight, the trend became apparent whilst children reached six months of age. At age four, the children in metformin group had higher BMI scores and were much more likely to satisfy the criteria for weight problems or overweight than children in placebo group.
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