Early Antiretroviral therapy linked with bone loss

A new study has discovered that early antiretroviral drugs ART causes bone loss compared with deferring ART.
Researchers examined HIV patients that used ART early and those that delayed treatment.

They discovered that early ART prevents HIV transmission but causes bone loss. Early treatment is also associated with increased bone loss of about 2-4%, this rate of bone loss will slow down after two years of treatment.

Antiretroviral drugs may cause broken bones as you get older, you can reduce the risk by engaging in simple exercise like walking and running.

Presently their is no cure for HIV, if you stop taking your drugs because of side effects of ART, your viral load will be high and the virus may become resistance to drug, you can manage the condition by taking calcium and vitamin D supplement to prevent osteoporosis.

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Human brain is one of the HIV reservoirs

Scientists have created a model that can monitor the movement and development of an HIV infection in the brain. HIV virus can move to brain of infected macrophage 14 days after infection.

Antiretroviral drugs cannot get into the brain easily, brain is one of the reservoirs of HIV virus. Scientists have confirmed that HIV can survive in another less-explored type of white blood cell.

It can also persist exclusively in macrophages, large white blood cells found in the liver, lung, bone marrow and brain. This is the reason why Antiretroviral drugs can suppress the virus but not being able to kill it.

There were some evidence of brain damage from early HIV infection. The
virus can still affect the brain even if there is undetectable levels of HIV in the blood.

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